Fast and affordable colorimetric precision nanodiagnostics
Nano4 Global is a young start-up launched in 2015 to market innovative nanotechnology based molecular diagnostics.
Nano4 is pioneering a new high-confidence proprietary nanotechnology platform relying on more than 12 years of research and development at Universidade NOVA de Lisboa - Science and Technology, Department of Life Sciences.
NANO4 is ISO 13485:2017 and ISO 9001:2015 Certified Company
NANO4 Global is ISO 13485:2017 and ISO 9001:2015 certified company, the higher level of ISO standards. These certifications are a requirement for regulatory purposes. ISO 13485:2017 is an international standard that outlines the requirements for a quality management system specific to the medical devices industry.
Certifications
Nano4 Industrial facility
Nano4 Global has a fully dedicated manufacturing lab. Located near Lisbon within a pharmaceutical campus hosting a Portuguese pharma company in Portugal. Nano4 Global manufacturing capability offer molecular diagnostic production and custom nanotechnology proficiency.
Nano4 Platform
How It Works
NANO4 Platform relies on a colorimetric molecular diagnostic method based on gold nanoparticles that provide fast and specific identification of a DNA or RNA biomarker.
NANO4 platform provides a colorimetric molecular diagnostic method based on gold nanoprobes that allow fast and specific identification of a DNA or RNA biomarker. The friendly use of Nano4 nanodiagnostics puts forward a fast, accurate, affordable technology - the next generation of molecular nanodiagnostics.
NANO4 is the next generation of molecular nanodiagnostics applied to life sciences that provides simple readout depending on the biomarker.
NANO4 is an award winning technology - Santander Totta/NOVAScientific Prize.
Gold nanoprobes provide a visual colorimetric change to identify the desired DNA/RNA sequence.
Advantages
fast colorimetric output
accurate
affordable and user friendly (no dedicated apparatus needed)
Turn Around Time
Due to the easy and simple operation, NANO4 will impact the way molecular diagnostics are performed and will lead the decentralization of molecular diagnostics - from genetics lab to point of need.
Visual Colorimetric Change
BLANK
Gold nanoprobes provide a
visual colorimetric change
that identifies a DNA/RNA
sequence.
POSITIVE
Target DNA/RNA prevents aggregation.
Solution remains
RED after revelator.
NEGATIVE
Gold nanoprobes aggregates
in contact with a revelator.
color changes
RED to BLUE
BLANK
Gold nanoprobes provide a
visual colorimetric change
that identifies a DNA/RNA
sequence.
POSITIVE
Target DNA/RNA prevents aggregation.
Solution remains
RED after revelator.
NEGATIVE
Gold nanoprobes aggregates
in contact with a revelator.
color changes
RED to BLUE
NANO4 platform is extremely flexible and easily adapted to a range of applications where specific DNA or RNA sequence is critical, such as detection of human pathogens (validation ongoing for M. tuberculosis, Zika), selected cancers and other genetic diseases.
R&D
Design
Development
Clinical Validation
TB
Zika
Leukaemia
Undisclosed Prog.
Team
Executive Management
Our combination of expertise in Science, industry and operations allows us to realize the immense potential of our technology. Together, Nano4 Global team accumulates more than 30 years of experience in the life sciences, from, research, start-ups to operations and management.
Pedro V. Baptista, PhD
CSO
15 years of Leading research in Nanotechnoloy Diagnostics / Thereapeutics.
Strong commitment to SMEs via EU funded instruments and joint funded projects; acting as expert for international science Boards.
12 years multi-country corporate experience in Genzyme, including Country Manager and International Management.
President of Portugal’s Biotech Industry Organization, MBA and Pharma Degree.
5 years experience in clinical diagnostic in corporate environment, Founder of 2 successful SMEs, including Molecular Diagnostics Start up built upon 10 years of molecular genetics research.
